Study on JNJ-101556143 for Treating Metastatic Prostate Cancer
Sponsor: Janssen Research & Development, LLC
Sponsor score: 60
ClinicalTrials ID:NCT07832292
This clinical trial is testing a new treatment, JNJ-101556143, to see how well it works in men with advanced prostate cancer that has spread and no longer responds to hormone therapy. The study will look at whether the treatment can shrink or eliminate tumors.
Patient Parameters
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Program Overview
The purpose of this study is to evaluate the effectiveness of a new drug, JNJ-101556143, in treating men with metastatic prostate cancer that has become resistant to hormone therapy. Researchers will measure how well the drug works by checking if it can shrink or make the tumors disappear in these patients.
Eligibility Criteria
Inclusion Criteria
- Must have a confirmed diagnosis of prostate cancer.
- Cancer must have spread and become resistant to hormone therapy, with a PSA level of 10 ng/mL or higher.
- Must show signs of cancer progression, such as increased PSA levels or new tumors in lymph nodes, bones, or other organs, while on hormone therapy.
- Must have had surgery or medication to lower testosterone levels and continue this treatment during the study.
- Must have stopped other cancer treatments, like chemotherapy or radiation, within a specified time before starting the study drug.
- Any side effects from previous cancer treatments must have improved to a mild level.
Exclusion Criteria
- Have uncontrolled kidney, pancreas, or liver disease, except for certain stable conditions.
- Have allergies or intolerances to the study drug or its ingredients.
- Have had major surgery or a serious injury within 28 days before starting the study drug.
- Have untreated spinal cord compression unless it has been treated and stable for 28 days.
- Have had an organ or bone marrow transplant.
Locations
| FACILITY | ZIP | CITY | STATE |
|---|---|---|---|
| Southern Urology LLC | 70508 | Lafayette | Louisiana |
| Greater Boston Urology | 02360 | Plymouth | Massachusetts |
| Associated Medical Professionals | 13210 | Syracuse | New York |
| The Conrad Pearson Clinic | 38138 | Germantown | Tennessee |
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